PSB Publications

January – December 2010

Click for abstracts and full references

Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor. By Estrozi LF, Boehringer D, Shan SO, Ban N, Schaffitzel C.
- Nat Struct Mol Biol. PMID: 21151118 - EMBL/UVHCI

Structure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activity. By El Bakkouri M, Gutsche I, Kanjee U, Zhao B, Yu M, Goret G, Schoehn G, Burmeister WP, Houry WA.
- Proc Natl Acad Sci. PMID: 21148420 - UVHCI/IBS

Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease. By Zaferani A, Vives RR, van der Pol P, Hakvoort JJ, Navis GJ, van Goor H, Daha MR, Lortat-Jacob H, Seelen MA, van den Born J.
- J Biol Chem. PMID: 21135110 - IBS

A hybrid structural model of the complete Brugia malayi cytoplasmic asparaginyl-tRNA synthetase. By Crepin T, Peterson F, Haertlein M, Jensen D, Wang C, Cusack S, Kron M.
- J Mol Biol. PMID: 21134380 - ILL/EMBL

Studies on the parameters controlling the stability of the TET peptidase superstructure from Pyrococcus horikoshii revealed a crucial role of pH and catalytic metals in the oligomerization process. By Rosenbaum E, Ferruit M, Durá MA, Franzetti B.
- Biochim Biophys Acta.
PMID: 21130903 - IBS

A structural study of norovirus 3C protease specifity - binding of a designed active site-directed peptide inhibitor. By Hussey RJ, Coates L, Gill RS, Erskine PT, Coker SF, Mitchell EP, Cooper JB, Wood SS, Broadbridge R, Clarke IN, Lambden PR, Shoolingin-Jordan PM.
- Biochemistry. PMID: 21128685 - ESRF

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41. By Sabin C, Corti D, Buzon V, Seaman MS, Lutje Hulsik D, Hinz A, Vanzetta F, Agatic G, Silacci C, Mainetti L, Scarlatti G, Sallusto F, Weiss R, Lanzavecchia A, Weissenhorn W.
- PLoS Pathog. PMID: 21124990 - UVHCI

Antitumor Activity of Pyridocarbazole and Benzopyridoindole Derivatives that Inhibit Protein Kinase CK2. By Prudent R, Moucadel V, Nguyen CH, Barette C, Schmidt F, Florent JC, Lafanechère L, Sautel CF, Duchemin-Pelletier E, Spreux E, Filhol O, Reiser JB, Cochet C.
- Cancer Res. PMID: 21118972 - IBS

Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70. By Vercheval L, Bauvois C, di Paolo A, Borel F, Ferrer JL, Sauvage E, Matagne A, Frère JM, Charlier P, Galleni M, Kerff F.
- Biochem J. PMID: 21108605 - IBS

Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): Functional similarities based on common structural features between two multispecific ABC proteins. By Bessadok A, Garcia E, Jacquet H, Martin S, Garrigues A, Loiseau N, Andre F, Orlowski S, Vivaudou M.
- J Biol Chem. PMID: 21098040 - IBS

Crystallographic snapshots of the reaction of aromatic C–H with O2 catalysed by a protein-bound iron complex. By Christine Cavazza, Constance Bochot, Pierre Rousselot-Pailley, Philippe Carpentier, Mickaël V. Cherrier, Lydie Martin, Caroline Marchi-Delapierre, Juan C. Fontecilla-Camps, Stéphane Ménage
- Nature Chem.
PMID: 21107372 - IBS

Nucleoprotein-RNA orientation in the measles virus nucleocapsid by three-dimensional electron microscopy. By Desfosses A, Goret G, Estrozi LF, Ruigrok RW, Gutsche I.
- J Virol. PMID: 21106738 - UVHCI/IBS/EMBL

Structural biology of protein functional regulation. By Dessen A, Xu W.
- Curr Opin Struct Biol. PMID: 21094598 - IBS

X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger. By Nachon F, Carletti E, Wandhammer M, Nicolet Y, Schopfer LM, Masson P, Lockridge O.
- Biochem J. PMID: 21091433 - IBS

The NACos protein ubinuclein negatively regulates the productive cycle of Epstein-Barr Virus in epithelial cells. by Gruffat H, Lupo J, Morand P, Boyer V, Manet E.
- J Virol. PMID: 21084479 - UVHCI

A plasmid-based multigene expression system for mammalian cells. By Kriz, A., Schmid, K., Baumgartner, N., Ziegler, U., Berger, I., Ballmer-Hofer, K. & Berger, P.
- Nature Comm. PMID: 21081918 - EMBL

Raman-assisted crystallography suggests a mechanism of x-ray-induced disulfide radical formation and reparation. By Carpentier P, Royant A, Weik M, Bourgeois D.
- Structure.
PMID: 21070940 - IBS/ESRF

Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae.By Du Y, He YX, Zhang ZY, Yang YH, Shi WW, Frolet C, Guilmi AM, Vernet T, Zhou CZ, Chen Y.
- J Struct Biol. PMID: 21055474 - IBS

CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site.By Duus K, Thielens NM, Lacroix M, Tacnet P, Frachet P, Holmskov U, Houen G.
- FEBS J. PMID: 21054788 - IBS

Crystallization and preliminary X-ray diffraction analysis of human cytosolic seryl-tRNA synthetase. By Artero JB, Teixeira SC, Mitchell EP, Kron MA, Forsyth VT, Haertlein M.
- Acta Crystallogr Sect F PMID: 21045311 - ILL/ESRF

Combined neutron and X-ray diffraction studies of DNA in crystals and solutions. By Leal RM, Callow S, Callow P, Blakeley MP, Cardin CJ, Denny WA, Teixeira SC, Mitchell EP, Forsyth VT.
- Acta Crystallogr D. PMID: 21041945 - ILL/ESRF

A neutron diffraction study of purple membranes under pressure. Rossand IG, Zaccai G, Fragneto G.
- Acta Crystallogr D. PMID: 21041943 - ILL

The case for an empirical ’high-throughput’ neutron scattering approach to protein dynamics. By Zaccai G.
- Acta Crystallogr D. PMID: 21041941 - ILL

Neutron macromolecular crystallography with LADI-III. By Blakeley MP, Teixeira SC, Petit-Haertlein I, Hazemann I, Mitschler A, Haertlein M, Howard E, Podjarny AD.
- Acta Crystallogr D. PMID: 21041937 - ILL/IBS

Sweet neutron crystallography. By Teixeira SC, Blakeley MP, Leal RM, Gillespie SM, Mitchell EP, Forsyth VT.
- Acta Crystallogr D. PMID: 21041928 - ILL/ESRF

Structure of the bacteriophage T4 long tail fiber receptor-binding tip. By Bartual SG, Otero JM, Garcia-Doval C, Llamas-Saiz AL, Kahn R, Fox GC, van Raaij MJ.
- Proc Natl Acad Sci. PMID: 21041684 - IBS

Divergent pathways lead to ESCRT-III-catalyzed membrane fission. By Peel S, Macheboeuf P, Martinelli N, Weissenhorn W.
- Trends Biochem Sci.
PMID: 21030261 - UVHCI

Bridging cell wall biosynthesis and bacterial morphogenesis. By Matteï PJ, Neves D, Dessen A.
- Curr Opin Struct Biol. PMID: 21030247 - IBS

Desorption electrospray ionization mass spectrometry of glycosaminoglycans and their protein noncovalent complex. By Przybylski C, Gonnet F, Hersant Y, Bonnaffé D, Lortat-Jacob H, Daniel R.
- Anal Chem.
PMID: 21028826 - IBS

Insights into Egg Coat Assembly and Egg-Sperm Interaction from the X-Ray Structure of Full-Length ZP3. By Han L, Monne M, Okumura H, Schwend T, Cherry AL, Flot D, Matsuda T, Jovine L.
- Cell.
PMID: 20970175 - EMBL/ESRF

Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein. By Boulo S, Akarsu H, Lotteau V, Müller CW, Ruigrok RW, Baudin F.
- Virology. PMID: 20974480 - UVHCI

A new functional sulfide oxidase-oxygen reductase supercomplex in the membrane of the hyperthermophilic bacterium Aquifex aeolicus. By Prunetti L, Infossi P, Brugna M, Ebel C, Giudici-Orticoni MT, Guiral M.
- J Biol Chem. PMID: 20971847 - IBS

The Extended Conformation of the 2.9-Å Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus. By Paracuellos P, Ballandras A, Robert X, Kahn R, Herve M, Mengin-Lecreulx D, Cozzone AJ, Duclos B, Gouet P.
- J Mol Biol. PMID: 20965199 - IBS

Combining Independent Drug Classes into Superior, Synergistically Acting Hybrid Molecules. By Müller-Schiffmann A, März-Berberich J, Andreyeva A, Ronicke R, Bartnik D, Brener O, Kutzsche J, Horn AH, Hellmert M, Polkowska J, Gottmann K, Reymann KG, Funke SA, Nagel-Steger L, Moriscot C, Schoehn G, Sticht H, Willbold D, Schrader T, Korth C.
- Angew Chem Int Ed Engl. PMID: 20922735 - IBS/UVHCI

Gradual Adaptive Changes of a Protein Facing High Salt Concentrations. By Coquelle N, Talon R, Juers DH, Girard E, Kahn R, Madern D.
- J Mol Biol. PMID: 20888835 - IBS

Effect of crowding on the conformation of interwound DNA strands from neutron scattering measurements and Monte Carlo simulations. By Zhu X, Ng SY, Gupta AN, Feng YP, Ho B, Lapp A, Egelhaaf SU, Forsyth VT, Haertlein M, Moulin M, Schweins R, van der Maarel JR.
- Phys Rev E Stat Nonlin Soft Matter Phys. PMID: 20866438 - ILL

Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription. By Reguera J, Weber F, Cusack S.
- PLoS Pathog.
PMID: 20862319 - EMBL

Relocation of Aurora B and Survivin from Centromeres to the Central Spindle Impaired by a Kinesin-Specific MKLP-2 Inhibitor. By Tcherniuk S, Skoufias DA, Labriere C, Rath O, Gueritte F, Guillou C, Kozielski F.
- Angew Chem Int Ed Engl. PMID: 20857469 - IBS

Optimization of conditions for the glycosyltransferase activity of penicillin-binding protein-1a from Thermotoga maritima. By Offant J, Terrak M, Derouaux A, Breukink E, Nguyen-Distèche M, Zapun A, Vernet T.
- FEBS J. PMID: 20849416 - IBS

Large scale purification of linear plasmid DNA for efficient high throughput cloning. By Noirclerc-Savoye M, Gallet B, Bernaudat F, Vernet T.
- Biotechnol J. PMID: 20845387 - IBS

A glycyl free radical as the precursor in the synthesis of carbon monoxide and cyanide by the [FeFe]-hydrogenase maturase HydG. By Nicolet Y, Martin L, Tron C, Fontecilla-Camps JC.
FEBS Lett. PMID: 20837009 - IBS

Structural and Functional Characterization of the Recombinant Human Mitochondrial Trifunctional Protein. By Fould B, Garlatti V, Neumann E, Fenel D, Gaboriaud C, Arlaud GJ.
- Biochemistry PMID: 20825197 - IBS

Diffusion pathways of oxygen species in the phototoxic fluorescent protein KillerRed. By Roy A, Carpentier P, Bourgeois D, Field M.
- Photochem Photobiol Sci. PMID: 20820672 – IBS/ESRF

Expression of soluble, active fragments of the morphogenetic protein SpoIIE from Bacillus subtilis using a library-based construct screen. By Rawlings AE, Levdikov VM, Blagova E, Colledge VL, Mas PJ, Tunaley J, Vavrova L, Wilson KS, Barak I, Hart DJ, Wilkinson AJ.
- Protein Eng Des Sel. PMID: 20817757 - EMBL

Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain. By Nadal M, Mas PJ, Blanco AG, Arnan C, Solà M, Hart DJ, Coll M.
- Proc Natl Acad Sci. PMID: 20805464 - EMBL

Conformational dynamics of the bovine mitochondrial ADP/ATP carrier isoform 1 revealed by hydrogen/deuterium exchange coupled to mass spectrometry. By Rey M, Man P, Clemencon B, Trezeguet V, Brandolin G, Forest E, Pelosi L.
- J Biol Chem. PMID: 20805227 - IBS

Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains: Implications for Actin Filament Nucleation. By Rebowski G, Namgoong S, Boczkowska M, Leavis PC, Navaza J, Dominguez R.
- J Mol Biol. PMID: 20804767 - IBS

Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase. By Zidar N, Tomašić T, Šink R, Rupnik V, Kovač A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Müller Premru M, Zega A, Gobec S, Peterlin Mašič L, Kikelj D.
- J Med Chem. PMID: 20804196 - IBS

Structure and RNA Interactions of the Plant MicroRNA Processing-Associated Protein HYL1. By Rasia RM, Mateos J, Bologna NG, Burdisso P, Imbert L, Palatnik JF, Boisbouvier J.
- Biochemistry.
PMID: 20735118 - IBS

Visualizing the Metal-Binding Versatility of Copper Trafficking Sites.By Badarau A, Firbank SJ, McCarthy AA, Banfield MJ, Dennison C.
- Biochemistry. PMID: 20726513 - EMBL

MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments. By Gabadinho J, Beteva A, Guijarro M, Rey-Bakaikoa V, Spruce D, Bowler MW, Brockhauser S, Flot D, Gordon EJ, Hall DR, Lavault B, McCarthy AA, McCarthy J, Mitchell E, Monaco S, Mueller-Dieckmann C, Nurizzo D, Ravelli RB, Thibault X, Walsh MA, Leonard GA, McSweeney SM.
- J Synchrotron Radiat. PMID: 20724792 - ESRF/EMBL

Regulation of NADPH oxidase activity in phagocytes - Relationship between FAD/NADPH binding and oxidase complex assembly.By Debeurme F, Picciocchi A, Dagher MC, Grunwald D, Beaumel S, Fieschi F, Stasia MJ.
- J Biol Chem. PMID: 20724480 - IBS

Maximum Likelihood based Classification of Electron Tomographic Data.By Stölken M, Beck F, Haller T, Hegerl R, Gutsche I, Carazo JM, Baumeister W, Scheres SH, Nickell S.
- J Struct Biol. PMID: 20719249 - UVHCI

Direct interaction between CD91 and C1q. By Duus K, Hansen EW, Tacnet P, Frachet P, Arlaud GJ, Thielens NM, Houen G.
- FEBS J.PMID: 20716178 - IBS

Specific cellular water dynamics observed in vivo by neutron scattering and NMR. By Jasnin M, Stadler A, Tehei M, Zaccai G.
- Phys Chem Chem Phys. PMID: 20714607 - ILL

Optimising diffusion-weighted imaging in the abdomen and pelvis: comparison of image quality between monopolar and bipolar single-shot spin-echo echo-planar sequences. By Kyriazi S, Blackledge M, Collins DJ, Desouza NM.
- Eur Radiol. PMID: 20711734 - IBS

Diffraction cartography: applying microbeams to macromolecular crystallography sample evaluation and data collection.By Bowler MW, Guijarro M, Petitdemange S, Baker I, Svensson O, Burghammer M, Mueller-Dieckmann C, Gordon EJ, Flot D, McSweeney SM, Leonard GA.
- Acta Crystallogr D. PMID: 20693684 - ESRF

Raman-assisted crystallography of biomolecules at the synchrotron: Instrumentation, methods and applications. By McGeehan JE, Bourgeois D, Royant A, Carpentier P.
- Biochim Biophys Acta.
PMID: 20691814 - IBS/ESRF

Dynamics characterization of fully hydrated bacterial cell walls by solid-state NMR: evidence for cooperative binding of metal ions. By Kern T, Giffard M, Hediger S, Amoroso A, Giustini C, Bui NK, Joris B, Bougault C, Vollmer W, Simorre JP.
- J Am Chem Soc. PMID: 20681725 - IBS

Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. By Reynoird N, Schwartz BE, Delvecchio M, Sadoul K, Meyers D, Mukherjee C, Caron C, Kimura H, Rousseaux S, Cole PA, Panne D, French CA, Khochbin S.
- EMBO J. PMID: 20676058 - EMBL

NMR structure and ion channel activity of the p7 protein from hepatitis C virus. By Montserret R, Saint N, Vanbelle C, Salvay AG, Simorre JP, Ebel C, Sapay N, Renisio JG, Bockmann A, Steinmann E, Pietschmann T, Dubuisson J, Chipot C, Penin F.
- J Biol Chem. PMID: 20667830 - IBS

Structural approaches of the mitochondrial carrier family. By Nury H, Blesneac I, Ravaud S, Pebay-Peyroula E.
- Methods Mol Biol. PMID: 20665263 - IBS


Crystallography of membrane proteins: from crystallization to structure. By Deniaud A, Moiseeva E, Gordeliy V, Pebay-Peyroula E.
- Methods Mol Biol. PMID: 20665262 - IBS


Structure and interactions of fish type III antifreeze protein in solution.  By Salvay AG, Gabel F, Pucci B, Santos J, Howard EI, Ebel C.
- Biophys J. PMID: 20643081 - IBS


The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3’-end processing of animal histone mRNAs. By Ruepp MD, Vivarelli S, Pillai RS, Kleinschmidt N, Azzouz TN, Barabino SM, Schümperli D.
- Nucleic Acids Res. PMID: 20634199 - EMBL


Electrochromism: a useful probe to study algal photosynthesis.  By Bailleul B, Cardol P, Breyton C, Finazzi G.
- Photosynth Res. PMID: 20632109 - IBS


In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?  By Moules V, Ferraris O, Terrier O, Giudice E, Yver M, Rolland JP, Bouscambert-Duchamp M, Bergeron C, Ottmann M, Fournier E, Traversier A, Boule C, Rivoire A, Lin Y, Hay A, Valette M, Marquet R, Rosa-Calatrava M, Naffakh N, Schoehn G, Thomas D, Lina B.
- Virology. PMID: 20627352 - UVHCI/IBS


New adhesin functions of surface-exposed pneumococcal proteins. By Frolet C, Beniazza M, Roux L, Gallet B, Noirclerc-Savoye M, Vernet T, Di Guilmi AM.
- BMC Microbiol. PMID: 20624274 - IBS


A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction. By Pompidor G, Maury O, Vicat J, Kahn R.
- Acta Crystallogr D. PMID: 20606256 - IBS


Pentacoordinated phosphorus revisited by high-level QM/MM calculations. By Marcos E, Field MJ, Crehuet R.
- Proteins. PMID: 20602355 - IBS


Crystallization of recombinant Bacteroides fragilis glutamine synthetase (GlnN) isolated using a novel and rapid purification protocol. By van Rooyen JM, Abratt VR, Belrhali H, Sewell BT.
- Protein Expr Purif. PMID: 20600942 - EMBL


Ab initio high-resolution single-particle 3D reconstructions: the Symmetry-Adapted-Functions way. By Estrozi LF, Navaza J.
- J Struct Biol. PMID: 20599509 - IBS/UVHCI


Combining methods for speeding up multi-dimensional acquisition. Sparse sampling and fast pulsing methods for unfolded proteins. By Marion D.
- J Magn Reson.
PMID: 20594882 - IBS


Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit. By Crépin T, Dias A, Palencia A, Swale C, Cusack S, Ruigrok RW.
- J Virol. PMID: 20592097 - UVHCI/EMBL


p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex. By Marcoux J, Man P, Petit-Haertlein I, Vives C, Forest E, Fieschi F.
- J Biol Chem. PMID: 20592030 - IBS


Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex. By Brier S, Pflieger D, Le Mignon M, Bally I, Gaboriaud C, Arlaud GJ, Daniel R.
- J Biol Chem. PMID: 20592021 - IBS


Characterization and binding activity of the chonDroitin / dermatan sulphate chain from Endocan, a soluble endothelial Proteoglycan. By Sarrazin S, Lyon M, Deakin JA, Guerrini M, Lassalle P, Delehedde M, Lortat-Jacob H.
PMID: 20581009 - IBS


Proteome analysis of microtubule-associated proteins and their interacting partners from mammalian brain. By Kozielski F, Riaz T, Debonis S, Koehler CJ, Kroening M, Panse I, Strozynski M, Donaldson IM, Thiede B.
- Amino Acids. PMID: 20567863 - IBS


Distinct oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand binding site. By Vincent F, Round A, Reynaud A, Bordi C, Filloux A, Bourne Y.
- Environ Microbiol. PMID: 20553556 - EMBL


Cutting Edge: C1q Binds Deoxyribose and Heparan Sulfate through Neighboring Sites of Its Recognition Domain. By Garlatti V, Chouquet A, Lunardi T, Vives R, Païdassi H, Lortat-Jacob H, Thielens NM, Arlaud GJ, Gaboriaud C.
- J Immunol. PMID: 20548024 - IBS


Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study By A Y. Kovalevsky, L.Hanson, S. Z. Fisher, M. Mustyakimov, S. A. Mason, V. T. Forsyth, M. P. Blakeley, D. A. Keen, T. Wagner, H.L. Carrell, A. K. Katz, J. P. Glusker, P. Langan
- Structure. PMID: 20541506 - ILL


Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. By Zheng K, Xiol J, Reuter M, Eckardt S, Leu NA, McLaughlin KJ, Stark A, Sachidanandam R, Pillai RS, Wang PJ.
- Proc Natl Acad Sci. PMID: 20534472 - EMBL


Influenza Virus Polymerase: Structural insights into replication and host adaptation mechanisms. By Boivin S, Cusack S, Ruigrok RW, Hart DJ.
- J Biol Chem. PMID: 20538599 - EMBL


Effect of crowding on the conformation of interwound DNA strands from neutron scattering measurements and Monte Carlo simulations By Xi. Zhu, S. Yee Ng, A. N. Gupta, Y. P. Feng, B. Ho, A. Lapp, S. U. Egelhaaf, V. T. Forsyth, Mi. Haertlein, M. Moulin, R. Schweins & J.R. C. van der Maarel.

Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies. By Petit-Haertlein I, Blakeley MP, Howard E, Hazemann I, Mitschler A, Podjarny A, Haertlein M.
- Acta Crystallogr F. PMID: 20516595 - ILL

Effective removal of nonionic detergents in protein mass spectrometry, hydrogen/deuterium exchange, and proteomics. By Rey M, Mrázek H, Pompach P, Novák P, Pelosi L, Brandolin G, Forest E, Havlícek V, Man P.
- Anal Chem. PMID: 20507168 - IBS

Measurement of Site-Specific (13)C Spin-Lattice Relaxation in a Crystalline Protein. By Lewandowski JR, Sein J, Sass HJ, Grzesiek S, Blackledge M, Emsley L.
- J Am Chem Soc. PMID: 20507068 - IBS

Co-chaperone interactions in export of the type III needle component PscF of Pseudomonas aeruginosa. By Ple S, Job V, Dessen A, Attree I.
- J Bacteriol.
PMID: 20494986 - IBS

Direct detection of CH/pi interactions in proteins. By Plevin MJ, Bryce DL, Boisbouvier J.
- Nat Chem.
PMID: 20489715 - IBS

Structure-function perturbation and dissociation of tetrameric urate oxidase by high hydrostatic pressure. By Girard E, Marchal S, Perez J, Finet S, Kahn R, Fourme R, Marassio G, Dhaussy AC, Prange T, Giffard M, Dulin F, Bonnete F, Lange R, Abraini JH, Mezouar M, Colloc’h N.
- Biophys J. PMID: 20483346 - IBS

Structure of the K-turn U4 RNA: a combined NMR and SANS study. By Falb M, Amata I, Gabel F, Simon B, Carlomagno T.
- Nucleic Acids Res. PMID: 20466811 - IBS

Crystal Structure of the Neutralizing Llama V(HH) D7 and Its Mode of HIV-1 gp120 Interaction. By Hinz A, Lutje Hulsik D, Forsman A, Koh WW, Belrhali H, Gorlani A, de Haard H, Weiss RA, Verrips T, Weissenhorn W.
- PLoS One. PMID: 20463957 - UVHCI/EMBL

Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions. By Buzon V, Natrajan G, Schibli D, Campelo F, Kozlov MM, Weissenhorn W.
- PLoS Pathog. PMID: 20463810 - UVHCI

Structural Disorder within Sendai Virus Nucleoprotein and Phosphoprotein: Insight into the Structural Basis of Molecular Recognition. By Jensen MR, Bernadó P, Houben K, Blanchard L, Marion D, Ruigrok RW, Blackledge M.
- Protein Pept Lett. PMID: 20450486 - UVHCI/IBS

Structural Disorder In Proteins Of The Rhabdoviridae Replication Complex. By Leyrat C, Gerard FC, de Almeida Ribeiro E Jr, Ivanov I, Ruigrok RW, Jamin M.
- Protein Pept Lett.
PMID: 20450482 - UVHCI/ILL

Macromolecular crystal data phased by negative-stained electron-microscopy reconstructions. By Trapani S, Schoehn G, Navaza J, Abergel C.
- Acta Crystallogr D. PMID: 20445226 - IBS

Crystallization of the membrane protein hVDAC1 produced in cell-free system. By Deniaud A, Liguori L, Blesneac I, Lenormand JL, Pebay-Peyroula E.
- Biochim Biophys Acta. PMID: 20435015 - IBS

Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX. By Mourao A, Varrot A, Mackereth CD, Cusack S, Sattler M.
- RNA. PMID: 20430857 - EMBL

The tripartite capsid gene of Salmonella phage Gifsy-2 yields a capsid assembly pathway engaging features from HK97 and lambda. By Effantin G, Figueroa-Bossi N, Schoehn G, Bossi L, Conway JF.
- Virology. PMID: 20427067 - UVHCI/IBS

Structural and functional characterization of human peripheral nervous system myelin protein P2. By Majava V, Polverini E, Mazzini A, Nanekar R, Knoll W, Peters J, Natali F, Baumgaertel P, Kursula I, Kursula P.
- PLoS One. PMID: 20421974 - IBS

Data storage based on photochromic and photoconvertible fluorescent proteins. By Adam V, Mizuno H, Grichine A, Hotta JI, Yamagata Y, Moeyaert B, Nienhaus GU, Miyawaki A, Bourgeois D, Hofkens J.
- J Biotechnol. PMID: 20416344 - IBS/ESRF

Complement protein C1q forms a complex with cytotoxic prion protein oligomers. By Erlich P, Dumestre-Perard C, Ling WL, Lemaire-Vieille C, Schoehn G, Arlaud GJ, Thielens NM, Gagnon J, Cesbron JY.
- J Biol Chem. PMID: 20410306 - IBS

Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation. By Carletti E, Colletier JP, Dupeux F, Trovaslet M, Masson P, Nachon F.
- J Med Chem. PMID: 20408548 - IBS/EMBL


New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights. By Lopez-Ramos M, Prudent R, Moucadel V, Sautel CF, Barette C, Lafanechere L, Mouawad L, Grierson D, Schmidt F, Florent JC, Filippakopoulos P, Bullock AN, Knapp S, Reiser JB, Cochet C.
- FASEB J .PMID: 20400536 - IBS

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain. By Hinz A, Miguet N, Natrajan G, Usami Y, Yamanaka H, Renesto P, Hartlieb B, McCarthy AA, Simorre JP, Goettlinger H, Weissenhorn W.
- Cell Host Microbe.PMID: 20399176 - UVHCI/IBS

A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria. By Robin AY, Cobessi D, Curien G, Robert-Genthon M, Ferrer JL, Dumas R.
- J Mol Biol. PMID: 20398676 - IBS/ESRF

X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate. Das A, Mahale S, Prashar V, Bihani S, Ferrer JL, Hosur MV.
- J Am Chem Soc. PMID: 20397633 - IBS/ESRF

Influence of chimeric human-bovine fibers on adenoviral uptake by liver cells and the antiviral immune response. By Rogee S, Grellier E, Bernard C, Jouy N, Loyens A, Beauvillain JC, Fender P, Corjon S, Hong SS, Boulanger P, Quesnel B, D’Halluin JC, Colin M.
- Gene Ther. PMID: 20393506 - UVHCI

Characterization of the cell-penetrating properties of the Epstein-Barr virus ZEBRA trans-activator. By Rothe R, Liguori L, Villegas-Mendez A, Marques B, Grunwald D, Drouet E, Lenormand JL.
- J Biol Chem. PMID: 20385549 - UVHCI

Structural basis of chaperone recognition of type III secretion system minor translocator proteins. By Job V, Mattei PJ, Lemaire D, Attree I, Dessen A.
- J Biol Chem. PMID: 20385547 - IBS

Crystallization and preliminary X-ray characterization of a catalytic and ATP-binding domain of a putative PhoR histidine kinase from the gamma-radioresistant bacterium Deinococcus radiodurans. By Caria S, de Sanctis D, Enguita FJ, McSweeney S.
- Acta Crystallogr F. PMID: 20383008 - ESRF

Temperature-dependent macromolecular X-ray crystallography. By Weik M, Colletier JP.
- Acta Crystallogr D. PMID: 20382997 - IBS

Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum. By Gill J, Kumar A, Yogavel M, Belrhali H, Jain SK, Rug M, Brown M, Maier AG, Sharma A.
- Malar J. PMID: 20377878 - EMBL

Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.. By Vijayakrishnan S, Kelly SM, Gilbert RJ, Callow P, Bhella D, Forsyth T, Lindsay JG, Byron O.
- J Mol Biol. PMID: 20361979 - ILL

Functional Characterization of the Recombinant Human C1 Inhibitor Serpin Domain: Insights into Heparin Binding. By Rossi V, Bally I, Ancelet S, Xu Y, Fremeaux-Bacchi V, Vives RR, Sadir R, Thielens N, Arlaud GJ.
- J Immunol. PMID: 20351192 - IBS

Prevalence and impact of occult hepatitis B infection in chronic hepatitis C patients treated with pegylated interferon and ribavirin. By Levast M, Larrat S, Thelu MA, Nicod S, Plages A, Cheveau A, Zarski JP, Seigneurin JM, Morand P, Leroy V.
- J Med Virol. PMID: 20336715 - UVHCI

Dynamics of heparan sulfate explored by neutron scattering. By Jasnin M, van Eijck L, Marek Koza M, Peters J, Laguri C, Lortat-Jacob H, Zaccai G.
- Phys Chem Chem Phys. PMID: 20336244 - IBS/ILL

Structural and Functional Analysis of the Engineered Type I DNA Methyltransferase EcoR124I(NT). By Taylor JE, Callow P, Swiderska A, Kneale GG.
- J Mol Biol. PMID: 20302878 - ILL

The Low-Temperature Inflection Observed in Neutron Scattering Measurements of Proteins Is Due to Methyl Rotation: Direct Evidence Using Isotope Labeling and Molecular Dynamics Simulations. By Wood K, Tobias DJ, Kessler B, Gabel F, Oesterhelt D, Mulder FA, Zaccai G, Weik M.
- J Am Chem Soc. PMID: 20302295 - IBS/ILL

The Adenovirus Type 3 Dodecahedron’s RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding. By Gout E, Schoehn G, Fenel D, Lortat-Jacob H, Fender P.
- J Biomed Biotechnol. PMID: 20224646 - IBS/UVHCI

Mechanism of hydrogen evolution catalyzed by NiFe hydrogenases: insights from a Ni-Ru model compound. By Vaccaro L, Artero V, Canaguier S, Fontecave M, Field MJ.
- Dalton Trans. PMID: 20221538 - IBS

A triclinic crystal form of Escherichia coli4-diphosphocytidyl-2C-methyl-D-erythritol kinase and reassessment of the quaternary structure. By Kalinowska-Tluscik J, Miallau L, Gabrielsen M, Leonard GA, McSweeney SM, Hunter WN.
- Acta Crystallogr F PMID: 20208151 - ESRF

ESPRIT: An automated, library-based method for mapping and soluble expression of protein domains from challenging targets. By Yumerefendi H, Tarendeau F, Mas PJ, Hart DJ.
- J Struct Biol. PMID: 20206698 - EMBL

TMKP1 is a novel wheat stress responsive MAP kinase phosphatase localized in the nucleus. By Zaïdi I, Ebel C, Touzri M, Herzog E, Evrard JL, Schmit AC, Masmoudi K, Hanin M.
- Plant Mol Biol. PMID: 20204675 - IBS

Biosynthesis and emission of insect-induced methyl salicylate and methyl benzoate from rice. By Zhao N, Guan J, Ferrer JL, Engle N, Chern M, Ronald P, Tschaplinski TJ, Chen F.
- Plant Physiol Biochem. PMID: 20199866 - IBS

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA. By Srivastava A, Gangnard S, Round A, Dechavanne S, Juillerat A, Raynal B, Faure G, Baron B, Ramboarina S, Singh SK, Belrhali H, England P, Lewit-Bentley A, Scherf A, Bentley GA, Gamain B.
- Proc Natl Acad Sci PMID: 20194779 - EMBL/ESRF

CopK from Cupriavidus metallidurans CH34 Binds Cu(I) in a Tetrathioether Site: Characterization by X-ray Absorption and NMR Spectroscopy. By Sarret G, Favier A, Covès J, Hazemann JL, Mergeay M, Bersch B.
- J Am Chem Soc. PMID: 20192263 - IBS

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA.

By Srivastava A, Gangnard S, Round A, Dechavanne S, Juillerat A, Raynal B, Faure G, Baron B, Ramboarina S, Singh SK, Belrhali H, England P, Lewit-Bentley A, Scherf A, Bentley GA, Gamain B.
- Proc Natl Acad Sci U S A PMID: 20194779 - EMBL

New baculovirus expression tools for recombinant protein complex production. By Trowitzsch S, Bieniossek C, Nie Y, Garzoni F, Berger I.
- J Struct Biol. PMID: 20178849 - EMBL

Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS. By Lebbink JH, Fish A, Reumer A, Natrajan G, Winterwerp HH, Sixma TK.
- J. Biol. Chem. PMID: 20167596 - UVHCI

Complement Protein C1q Recognizes Enzymatically Modified Low-Density Lipoprotein through Unesterified Fatty Acids Generated by Cholesterol Esterase. By Biro A, Ling WL, Arlaud GJ.
- Biochemistry. PMID: 20166680 - IBS

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by Formula rather than by phosphoranes.. By Baxter NJ, Bowler MW, Alizadeh T, Cliff MJ, Hounslow AM, Wu B, Berkowitz DB, Williams NH, Blackburn GM, Waltho JP.
- Proc Natl Acad Sci PMID: 20164409 - ESRF

Stereospecific Isotopic Labeling of Methyl Groups for NMR Spectroscopic Studies of High-Molecular-Weight Proteins.

By Gans P, Hamelin O, Sounier R, Ayala I, Dura MA, Amero CD, Noirclerc-Savoye M, Franzetti B, Plevin MJ, Boisbouvier J.
- Angew Chem Int Ed Engl. PMID: 20157899 - IBS

Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings. By Vajpai N, Gentner M, Huang JR, Blackledge M, Grzesiek S.
- J Am Chem Soc. PMID: 20155903 - IBS

Structural Basis of Host Cell Recognition by the Pilus Adhesin from Streptococcus pneumoniae.

By Izore T, Contreras-Martel C, El Mortaji L, Manzano C, Terrasse R, Vernet T, Di Guilmi AM, Dessen A.
- Structure. PMID: 20152157 - IBS


A TNF-like Trimeric Lectin Domain from Burkholderia cenocepacia with Specificity for Fucosylated Human Histo-Blood Group Antigens. By O. Sulak, G. Cioci, M. Delia, M. Lahmann, A. Varrot, A. Imberty & M. Wimmerov
- Structure.
PMID: 20152153 - ESRF


Stability and assembly of pilus subunits of streptococcus pneumoniae.

By El Mortaji L, Terrasse R, Dessen A, Vernet T, Di Guilmi AM.
- J Biol Chem. PMID: 20147289 - IBS


Editing Mechanism of Aminoacyl-tRNA Synthetases Operates by a Hybrid Ribozyme/Protein Catalyst.

By Hagiwara Y, Field MJ, Nureki O, Tateno M.
- J Am Chem Soc. PMID: 20136139 - IBS


Low-temperature switching by photoinduced protonation in photochromic fluorescent proteins.

By Faro AR, Adam V, Carpentier P, Darnault C, Bourgeois D, de Rosny E.
- Photochem Photobiol Sci. PMID: 20126803 - IBS/ESRF


A micromolar O-sulfated thiohydroximate inhibitor bound to plant myrosinase.

By Besle, A., Brazzolotto, X., Tatibouet, A., Cerniauskaite, D., Gallienne, E., Rollin, P. & Burmeister, W.P.
- Acta Crystallogr.
PMID: 20124710 - UVHCI



Evidence for conformational changes upon copper binding to Cupriavidus metallidurans CzcE.

By Petit-Haertlein I, Girard E, Sarret G, Hazemann JL, Gourhant P, Kahn R, Coves J.
- Biochemistry. PMID: 20112954 – IBS


Lactococcus lactis, an alternative system for functional expression of peripheral and intrinsic Arabidopsis membrane proteins.

By Frelet-Barrand A, Boutigny S, Moyet L, Deniaud A, Seigneurin-Berny D, Salvi D, Bernaudat F, Richaud P, Pebay-Peyroula E, Joyard J, Rolland N.
- PLoS One. PMID: 20098692 - IBS


Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.

By Corti D, Langedijk JP, Hinz A, Seaman MS, Vanzetta F, Fernandez-Rodriguez BM, Silacci C, Pinna D, Jarrossay D, Balla-Jhagjhoorsingh S, Willems B, Zekveld MJ, Dreja H, O Sullivan E, Pade C, Orkin C, Jeffs SA, Montefiori DC, Davis D, Weissenhorn W, McKnight A, Heeney JL, Sallusto F, Sattentau QJ, Weiss RA, Lanzavecchia A.
- PLoS One PMID: 20098712 - UVHCI


A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology.

By Durrant JD, Amaro RE, Xie L, Urbaniak MD, Ferguson MA, Haapalainen A, Chen Z, Di Guilmi AM, Wunder F, Bourne PE, McCammon JA.
- PLoS Comput Biol. PMID: 20098496 - IBS


Biophysical characterization and mutational analysis of the antibiotic resistance protein NimA from Deinococcus radiodurans.

By Leiros HK, Brandsdal BO, McSweeney SM.
- Biochim Biophys Acta.
PMID: 20096385 - ESRF

Structure of the dimerisation domain of the rabies virus phosphoprotein. By Ivanov I, Crepin T, Jamin M, Ruigrok RW.
- J Virol. PMID: 20089657 - UVHCI

Structural and mechanistic insights into Helicobacter pylori NikR activation. By Bahlawane C, Dian C, Muller C, Round A, Fauquant C, Schauer K, de Reuse H, Terradot L, Michaud-Soret I.
- Nucleic Acid Res. PMID:20089510 - IBS/ESRF

Getting a Grip on Complexes By Nie Y., Viola C., Bieniossek C., Trowitzsch S., Vijayachandran L. S., Chaillet M.,Garzoni F. & Berger I.
- Current Genomics - EMBL

Inhibition of DC-SIGN-Mediated HIV Infection by a Linear Trimannoside Mimic in a Tetravalent Presentation.

By Sattin S, Daghetti A, Thepaut M, Berzi A, Sánchez-Navarro M, Tabarani G, Rojo J, Fieschi F, Clerici M, Bernardi A.
- ACS Chem Biol. PMID: 20085340 - IBS

Defining Conformational Ensembles of Intrinsically Disordered and Partially Folded Proteins Directly from Chemical Shifts. By Jensen MR, Salmon L, Nodet G, Blackledge M.
- J Am Chem Soc. PMID: 20063887 - IBS

Enhanced Conformational Space Sampling Improves the Prediction of Chemical Shifts in Proteins. By Markwick PR, Cervantes CF, Abel BL, Komives EA, Blackledge M, McCammon JA.
- J Am Chem Soc. PMID: 20063881 - IBS

Towards an atomic resolution understanding of the influenza virus replication machinery. By Ruigrok RW, Crepin T, Hart DJ, Cusack S.
- Curr Opin Struct Biol. PMID: 20061134 - EMBL/UVHCI

The TDRD9-MIWI2 complex is essential f-or piRNA-mediated retrotransposon silencing in the mouse male germline. By Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.
- Dev Cell. PMID: 20059948 - EMBL

The SciZ protein anchors the enteroaggregative Escherichia coli Type VI secretion system to the cell wall. By Aschtgen MS, Gavioli M, Dessen A, Lloubes R, Cascales E.
- Mol Microbiol.
PMID: 20059692 - IBS

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein. By Gely S, Lowry DF, Bernard C, Jensen MR, Blackledge M, Costanzo S, Bourhis JM, Darbon H, Daughdrill G, Longhi S.
- J Mol Recognit. PMID: 20058326 - IBS

Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements. By Man P, Montagner C, Vitrac H, Kavan D, Pichard S, Gillet D, Forest E, Forge V. By Corazza A, Rennella E, Schanda P, Mimmi MC, Cutuil T, Raimondi S, Giorgetti S, Fogolari F, Viglino P, Frydman L, Gal M, Bellotti V, Brutscher B, Esposito G.
- FEBS J. PMID: 20050921 - IBS

Neutron Diffraction Studies of a Class A beta-Lactamase Toho-1 E166A/R274N/R276N Triple Mutant.

By Tomanicek SJ, Blakeley MP, Cooper J, Chen Y, Afonine PV, Coates L.
- J Mol Biol. PMID: 20036259 - ILL

Guidelines for the use of band-selective radiofrequency pulses in hetero-nuclear NMR: example of longitudinal-relaxation-enhanced BEST-type 1H-15N correlation experiments. By Lescop E, Kern T, Brutscher B.
- J Magn Reson. PMID: 20031460 - IBS

Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real time 2D NMR. By Corazza A, Rennella E, Schanda P, Mimmi MC, Cutuil T, Raimondi S, Giorgetti S, Fogolari F, Viglino P, Frydman L, Gal M, Bellotti V, Brutscher B, Esposito G.
- J Biol Chem. PMID: 20028983 - IBS

Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments. By Schaffitzel C, Postberg J, Paeschke K, Lipps HJ.
- Methods Mol Biol. PMID: 20012422 - EMBL

Red wine polyphenols cause growth inhibition and apoptosis in acute lymphoblastic leukaemia cells by inducing a redox-sensitive up-regulation of p73 and down-regulation of UHRF1. By Sharif T, Auger C, Alhosin M, Ebel C, Achour M, Etienne-Selloum N, Fuhrmann G, Bronner C, Schini-Kerth VB.
- Eur J Cancer PMID: 20074931 - IBS

Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments.

By Schaffitzel C, Postberg J, Paeschke K, Lipps HJ.
- Methods Mol Biol. PMID: 20012422 - EMBL

Investigation of gammaE-crystallin target protein binding to bovine lens alpha-crystallin by small-angle neutron scattering. By Clarke MJ, Artero JB, Moulin M, Callow P, Carver JA, Griffiths PC, Haertlein M, Harding JJ, Meek KM, Timmins P, Regini JW.
- Biochim Biophys Acta. PMID: 20004233 - ILL