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PSB

Carl-Ivar Brändén building (CIBB)
71, Avenue des Martyrs
CS 90181
F-38042 Grenoble
Intranet

Cryobench

Purpose of the platform (operated by IBS & ESRF)

Platform for UV-visible spectroscopy on nano-volume biological samples

typically protein crystals and solutions, from cryo- to room-temperatures

- Absorption microspectrophotometry.

- Fluorescence microspectrophotometry.

- Fluorescence lifetime measurements

- Raman microspectrometry.

- Actinic (laser) excitation of photosensitive samples.

Typical applications include:


- Monitoring oxidation state in metalloproteins.

- Monitoring X-ray induced radiation damage

- Monitoring the binding of ligands in protein crystals

- Kinetic crystallography.

- Test bench for online spectroscopic experiments on the ESRF MX beamlines


Responsible

Antoine Royant


Staff in charge of the platform

Off-line facility:
Antoine Royant – phone: 04 38 78 96 28 / 04 76 88 17 46
- antoine.royant@ibs.fr

On-line microspectrophotometer (absorption, fluorescence): Martin Weik – phone: 04 38 78 95 69
- martin.weik@ibs.fr

On-line Raman spectrometer :
Daniele de Sanctis – phone: 04 76 88 28 69 - daniele.de_sanctis@esrf.fr


In practice

- Location: ESRF - ID29
Access mode: Service and collaboration
Cost for PSB users: Free of charge
How to make a request: e-mail to cryobench_booking@esrf.fr.