SPR

Purpose of the platform (operated by IBS in collaboration with ESRF & UVHCI)

Biacore systems

The IBS operates three Biacore machines:

 one Biacore 1000 upgraded
 one Biacore X
 one Biacore 3000

The ESRF and UVHCI operate one Biacore machine:

 one Biacore X

These four systems use Surface Plasmon Resonance (SPR) to detect any binding events between two molecules, one of which being immobilized on a chip surface. Main applications are: analysis of binding specificity, affinity measurements, kinetic analysis, screening and competition analysis, epitope and binding site mapping, ligand fishing and supramolecular assembly studies.

Website

webpage of the platform

Responsible

IBS

Nicole Thielens
Hugues Lortat-Jacob

CIBB

Stéphane Boivin
Tel.: 04 76 20 94 12 or 04 76 20 94 42

Staff in charge of the platform

IBS: Nicole Thielens
CIBB: Stéphane Boivin

In practice

 Location:
IBS-LEM room 6336 (Biacore 3000, Biacore 1000 and Biacore X)
CIBB 1st floor room 103 (Biacore X)
 Access mode: collaboration
 How to make a request:
— for inexperienced users: contact Nicole Thielens
— for experienced users: contact Nicole Thielens (IBS machines) or Stéphane Boivin (CIBB machine) for booking and maintenance.