SPR

Purpose of the platform (operated by IBS in collaboration with ESRF & UVHCI)

Biacore systems

The IBS operates four Biacore machines:

 one Biacore T200
 two Biacore 3000
 one Biacore X

The ESRF and UVHCI operate one Biacore machine:

 one Biacore X

These four systems use Surface Plasmon Resonance (SPR) to detect any binding events between two molecules, one of which being immobilized on a chip surface. Main applications are: analysis of binding specificity, affinity measurements, kinetic analysis, screening and competition analysis, epitope and binding site mapping, ligand fishing and supramolecular assembly studies.

Website

webpage of the platform

Responsible

IBS

Nicole Thielens and Isabelle Bally

Staff in charge of the platform

IBS: Nicole Thielens and Isabelle Bally

In practice

 Location:_ IBS-IRPAS room 6336 (Biacore 3000, Biacore T200 and Biacore X) and CIBB 1st floor room 103 (Biacore X)

 Access mode:

• open to academics according to term to define.
• open to industrials on a service basis and depending on the availability of the instruments.

 How to make a request for the IBS machines: