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PSB

Carl-Ivar Brändén building (CIBB)
71, Avenue des Martyrs
CS 90181
F-38042 Grenoble
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SANS/SAXS

Purpose of the platform (operated by ILL and ESRF in collaboration with EMBL)

Small angle scattering instruments available for biology at PSB partner institutes include D22 and BM29. They are operated by ILL and ESRF/EMBL staff, respectively. Access is via a peer-reviewed proposal submission system at ILL and ESRF, either separately or with the possibility to ask for a joint SAXS/SANS experiment. While BM29 is dedicated exclusively to biological experiments (BioSAXS), about 10-15% of the D22/D11 instrument beamtime is dedicated to biology.
D22, D11 are small-angle neutron scattering instruments at ILL. Their q-range and high flux are ideal for studying most of biological macromolecular complexes and the variation of contrast (hydrogen/deuterium mix) enables to selectively observe the components involved in such complexes. Some sample environments (22-positions low-volume sample changer) and side equipments (temperature control, UV-Visible spectrophotometer) are also specifically designed for biological applications.
BM29 is a recently upgraded fully automated high throughput beamline at the ESRF dedicated to macromolecules in solution. It is operating with a sample changer robot or alternatively on-line size exclusion chromatography device both modes with automated data analysis for quality control and feedback. The improved beam characteristics result in reduced parasitic scattering, shorter exposure times (by a factor 10)


In practice

Location:
Location D22, D11 – Guide hall n°2, cold guide H512;
BM29 beamline is located in ESRF Experiment hall 1
Access mode:
ESRF "SANS" BAG that enables users to access the SANS/SAXS platform through a single entry point via the ILL proposal system.