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PSB

Carl-Ivar Brändén building (CIBB)
71, Avenue des Martyrs
CS 90181
F-38042 Grenoble
Intranet

Biophysical Platform

1.Purpose of the Platform



- Size and shape of macromolecules
- Stoichiometry of macromolecular assemblies
- Secondary and tertiary structure of macromolecules
- Thermodynamic stability of macromolecules
- Properties kinetic and thermodynamic interactions


Quality control of sample before experiment: We need SDS-PAGE image and UV 260/280 spectrum for each sample

Follow up / acknowledgements

Acknowledgements in publications and oral presentations

Acknowledgements in publications: "This work used the platforms of the Grenoble Instruct center (ISBG; UMS 3518 CNRS-CEA-UJF-EMBL) with support from FRISBI (ANR-10-INSB-05-02) and GRAL (ANR-10-LABX-49-01) within the Grenoble Partnership for Structural Biology (PSB)."


2.Webpage of the Platform

The platform can advise you or direct you on your choices and give you information on:

* Experimental constraints and duration of the experiments
* Estimations and calculations of physico-chemical parameters
* Methodological links and softwares to be used

NATURE OF THE PRESTATION

The platform can interact with users in three ways:

1) Service: routine experiments performed in standard conditions, without intervention of the person who requests them

2) Instrument allocation after user training: for users who have successfully completed training to gain operational autonomy allowing them to perform and/or analyze their experiments by themselves

3) Scientific collaboration: projects in which the Biophysical platform is strongly involved (several weeks to several years). In this case, experiments are designed, performed and analyzed in tandem between the scientific responsible and the applicant.


3.Responsible

Caroline Mas Biophysical Platfom Manager Ph: 33-(0)476209485
Marc JAMIN (Pr. UJF) - UVHCI : UMI 3265 UJF-EMBL-CNRS - Ph: 33-(0)476209462


5.Innstruments available

How to access each machine of the platforms:

SEC-MALLS
iTC 200
CD
Fluorimeter
MST
DLS

Satisfaction Survey


6.Booking

Note that in the absence of the platform manger:
  • Access is restricted to autonomous users
  • Validation of booking requests might be delayed

TO MAKE A BOOKING REQUEST, PLEASE FILL THE REQUEST FORM HERE

SEC-MALLS booking

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CD booking

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Fluorimeter booking

MST booking

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ITC200