Carl-Ivar Bränden building (CIBB)
71, Avenue des Martyrs
CS 90181
F-38042 Grenoble

The In Crystallo Optical Spectroscopy Laboratory (icOS)

Purpose of the platform (operated by IBS & ESRF)

The icOS Lab (previously known as the Cryobench) is dedicated to various types of optical spectroscopy experiments on macromolecular crystals. The central device is a microspectrophotometer that allows the lab to offer

UV/vis absorption spectroscopy,
fluorescence (emission) spectroscopy,->]
fluorescence lifetime measurements,
Raman spectroscopy,

...of protein crystals mounted on a goniometer between three objectives, usually cooled by a cryogenic stream.

Additionally, it will soon be possible to perform spectroscopic experiments directly at X-ray beamlines:

online UV/vis and fluorescence spectroscopy (on MASSIF-3 and FIP2),
online Raman spectroscopy (on ID30B).


Antoine Royant

Staff in charge of the platform

Antoine Royant

Phone +33 (0)4 76 88 17 46

In practice

Beamtime applications

Click hereto find out how to apply for experiments at the icOS lab.