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PSB

Carl-Ivar Bränden building (CIBB)
71, Avenue des Martyrs
CS 90181
F-38042 Grenoble
Intranet

Technical Platforms

PSB platforms

A UNIQUE PALETTE OF TECHNOLOGICAL PLATFORMS

PROTEIN EXPRESSION



Cell Free (operated by IBS)
www.isbg.fr/samples-preparation/cell-free-666

Deuteration Lab (operated by ILL)
www.ill.eu/users/support-labs-infrastructure/deuteration-laboratory

ESPRIT (operated by IBS)
www.isbg.fr/samples-preparation/esprit

Eukaryotic Expression Facility (operated by EMB)
https://embl.fr/services/eef

SAMPLE CHARACTERISATION



Cellular imaging (operated by IBS)
www.isbg.fr/cellular-analysis/cellular-imaging

Mass Spectrometry (operated by IBS)
www.isbg.fr/samples-preparation/mass-spectrometry

Molecular Biophysics platform (operated by IBS)
AUC, BLI, CD, DLS, Fluorimeter, ITC, MST, MP, PAOL, SEC-MALLS, SPR
www.isbg.fr/biophysics-characterisation

3-D STRUCTURE ANALYSIS



ESRF Structural Biology Beamlines (operated by ESRF)
www.esrf.eu/UsersAndScience/Experiments/MX/About_our_beamlines

FIP2 Beamline (BM07) (operated by IBS)
www.fip2-bm07.fr

High Field NMR (operated by IBS)
www.isbg.fr/structural-analysis/nmr

Neutron Diffraction instruments (operated by ILL)
D19, LADI-III & DALI
www.ill.eu/d19
www.ill.eu/instruments-support/instruments-groups/instruments/ladi-iii/characteristics
www.ill.eu/fr/users/instruments/instruments-list/dali/characteristics

The in crystallo Optical Spectroscopy Laboratory
www.esrf.eu/home/UsersAndScience/Experiments/MX/icOS.html

PROTEIN CRYSTALLISATION



HT Crystallisation (operated by EMBL)
https://htxlab.embl.fr

HT Membrane Protein Crystallisation (operated by IBS)
www.isbg.fr/protein-crystallisation/high-throughput-membrane-protein

SUPRAMOLECULAR STRUCTURE



Cryo-EM Titan Krios (operated by ESRF, IBS, EMBL & ILL)
www.esrf.eu/home/UsersAndScience/Experiments/MX/About_our_beamlines/CM01.html

Electron microscopy platform (operated by IBS)
www.isbg.fr/structural-analysis/cryo-electron-microscopy

SAXS/SANS (operated by ESRF & ILL)
www.esrf.eu/home/UsersAndScience/Experiments/MX/About_our_beamlines/
bm29.html

www.ill.eu/instruments-support/instruments-groups/instruments/d22
www.ill.eu/users/instruments/instruments-list/d11