FIP2-BM07 is the French ESRF beamline for protein crystallography. FIP2 is the former FIP-BM30A beamline, which has moved to port BM07 between 2019 and 2021 due to the ESRF upgrade. FIP benefits from a strong upgrade of the optics (repolished mirrors, coders on all moving axes) and a modern Pilatus 6M detector.
FIP2 can be used either for single or multi-wavelength diffraction (SAD, MAD) experiments. Its optics deliver a focused beam on a fixed sample position, with an energy resolution of about 10-3 to 10-4 and a large accessible energy range (5-25 keV). The beam intensity is 1e12 photons/(0.3x0.3 mm2).
FIP2 is a highly automated beamline, with a unique robotized experiment setup. Indeed, apart the robotized sample changer, FIP possesses also a plate screening system (G-Rob) for direct in situ analysis of crystals in the X-ray beam. With this system, it is possible to analyze crystals in sitting drop crystallization plates or microchips. This is specifically interesting for crystals too small to be fished, or too fragile to be handled or frozen. A rapid screening to determine the nature of the object to be analyzed (salt or protein crystals), collecting few frames for cell determination, or even complete data collection are possible.
Access mode
FIP2 is accessible to:
French academic users, through a national program committee,
European academic users, through the ESRF scientific review committee,
industrial users (direct access, no selection process, limited to a 10% quota).
Cost
The access to FIP is free for academic users, and fee-based (rate fixed by the ESRF) for industrial users.
Location
FIP2 (French beamline for Investigation of Proteins) is located on a Bending Magnet section 07 (BM07) of ESRF.
How to make a request ?
Apply now for beamtime through the Soleil synchrotron interface!
