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EMBO Practical Course – Structure, dynamics and function of biological macromolecules by NMR

Event date : 30 Aug – 6 Sep 2024

NMR spectroscopy is an essential technique that allows to study the structure, dynamics and interactions of macromolecules at atomic resolution. It is unique in extracting dynamic information over a large range of time scales and, therefore, in revealing the molecular mechanisms that control biological function. Recent developments in the NMR field include the study of intrinsically disordered proteins and their interaction mechanisms, atomic resolution insight into dynamics of RNA, real-time monitoring of megadalton nano-machines in action and studies of the conformational behaviour of proteins in living cells (in-cell NMR). The course will contribute to the advancement of this important field by providing a solid knowledge foundation for the next-generation NMR spectroscopists. It will include the theory of NMR and pulse sequence building blocks, structure determination strategies, relaxation techniques to study multi-timescale dynamics as well as the latest developments in in-cell NMR. The emphasis of this EMBO Practical Course is on practical skills i.e. hands-on experience in the setup, processing and analysis of NMR experiments and in deriving quantitative structural and dynamic information.

For more information about the course and the programme: https://meetings.embo.org/event/24-nmr