EPN Campus, Grenoble
Duration: 1 week – 30 h (25 h lectures + 5 h exercises)
This one-week course will explore the physical principles governing the behavior of biological macromolecules in solution.
Topics covered during the week include:
- Intermolecular interactions (electrostatics, depletion, hydration forces)
- Macromolecular motions, conformational changes, binding, and assembly
- Protein and RNA folding and folding kinetics
- Intrinsically disordered proteins and NMR approaches
- Enzymology, allostery, cooperativity, and metabolic regulation
- Weak interactions in biology
- Conformations and dynamics of proteins (H/D exchange, MD simulations)
- Macromolecules in solution and liquid–liquid phase separation
- Integrative structural biology approaches
Guest speakers include:
- Kristina Djinovic-Carugo (EMBL Grenoble)
- Thomas Zemb (CEA)
- Robert Schneider (CEA)
- Judith Peters (UGA-ILL)
- Jean-Marie Bourhis (IBS)
- Christine Ebel (IBS)
This course completes a two-part overview of modern molecular biophysics. The two parts are designed to alternate every other year, and attendance to Part I is not required to attend Part II.
If you wish to register, please contact:
Caroline Mas (caroline.mas@ibs.fr)
Marc Jamin (marc.jamin@ibs.fr)